Investigating the Implications of a Variable RBE on Proton Dose Fractionation Across a Clinical Pencil Beam Scanned Spread-Out Bragg Peak
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چکیده
منابع مشابه
Investigating the Implications of a Variable RBE on Proton Dose Fractionation Across a Clinical Pencil Beam Scanned Spread-Out Bragg Peak.
PURPOSE To investigate the clinical implications of a variable relative biological effectiveness (RBE) on proton dose fractionation. Using acute exposures, the current clinical adoption of a generic, constant cell killing RBE has been shown to underestimate the effect of the sharp increase in linear energy transfer (LET) in the distal regions of the spread-out Bragg peak (SOBP). However, experi...
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Introduction: Depth-dose distribution curve of protons in the matter has a maximum is called Bragg peak. Bragg peak of a monoenergetic proton beam is too narrow. The spread out Bragg peak should be created for full coverage of the tumor. The spread out Bragg peak is obtained in the depth of the tumor with superposition of the several Bragg peaks. The aim of this study was coverage of an eye tum...
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ژورنال
عنوان ژورنال: International Journal of Radiation Oncology*Biology*Physics
سال: 2016
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2016.02.029